Review
doi: 10.3724/sp.j.1005.2011.01300.
[Regulation of gene expression during spermatogenesis at transcriptional level]
[Article in
Chinese]
Affiliations
- PMID: 22207375
- DOI: 10.3724/sp.j.1005.2011.01300
Item in Clipboard
Review
[Regulation of gene expression during spermatogenesis at transcriptional level]
[Article in
Chinese]
Yi Chuan.
2011 Dec.
Abstract
Mammalian spermatogenesis is a highly complex cell division and differentiation process occurring in the seminiferous tubules of the testis. This processes are regulated at both transcriptional and post-transcriptional levels, any mistake in this process can lead to infertility. Unveiling the molecular mechanisms of spermatogenesis has important implications for exploring novel contraceptive approach and treatment of infertility. This review addresses recent progress towards understanding the regulation of androgen, estrogen and their receptors, transcription factors and chromatin-associated factors for spermatogenesis at transcriptional level.
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