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Review
. 2012 Aug;18(4):331-8.
doi: 10.1007/s13365-011-0074-x. Epub 2011 Dec 30.

Neuromuscular complications in HIV: effects of aging

Jessica Robinson-Papp  1 , Ik Lin Tan, David M Simpson
Affiliations
Review

Neuromuscular complications in HIV: effects of aging

Jessica Robinson-Papp et al. J Neurovirol. 2012 Aug.

Abstract

There has been speculation that chronic HIV infection is a condition of accelerated aging that may lead to early onset of disease in multiple organ systems. The neuromuscular disorders of HIV, in particular distal symmetric polyneuropathy and myopathies, are also seen in the general population among older patients. As the HIV-infected population ages, there may be deleterious synergistic effects of age and chronic HIV infection on the brain, peripheral nerve, and muscle. In this review, we explore commonalities between the clinical features and putative mechanisms of neuromuscular disorders and HIV.

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