[Vitamin D and autoimmunity. Second part: Clinical aspects]
- PMID: 22209319
- DOI: 10.1016/j.revmed.2011.11.010
[Vitamin D and autoimmunity. Second part: Clinical aspects]
Abstract
Vitamin D is often confined to its role in calcium homeostasis and bone metabolism. An exponential literature discusses its non-skeletal effects, especially its central role in the physiology of the immune system, where it acts at several levels to maintain self-tolerance. Here, the authors review the experimental, epidemiological and clinical studies, illustrating the potential role of vitamin D in the development and perpetuation of autoimmune diseases such as systemic lupus erythematosus, type 1 diabetes mellitus, multiple sclerosis, inflammatory bowel diseases or rheumatoid arthritis.
Copyright © 2011 Société nationale française de médecine interne (SNFMI). Published by Elsevier SAS. All rights reserved.
Comment in
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[Sun and rheumatoid arthritis].Rev Med Interne. 2012 Jun;33(6):351. doi: 10.1016/j.revmed.2012.03.358. Epub 2012 May 8. Rev Med Interne. 2012. PMID: 22572586 French. No abstract available.
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