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Review
. 2012 Feb;24(1):57-63.
doi: 10.1016/j.ceb.2011.12.003. Epub 2011 Dec 29.

Kinetochore dynamics: how protein dynamics affect chromosome segregation

Jonas F Dorn  1 , Paul S Maddox
Affiliations
Review

Kinetochore dynamics: how protein dynamics affect chromosome segregation

Jonas F Dorn et al. Curr Opin Cell Biol. 2012 Feb.

Abstract

Protein dynamics generate adaptive cellular architecture. This concept is exemplified by kinetochores, organelles that orchestrate chromosome segregation during mitosis. In this review, we will focus on protein dynamics at kinetochores and discuss how these dynamics impact chromosome motility during mitosis.

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