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. 1979 Apr 12;46(1-2):17-24.
doi: 10.1007/BF00684799.

Neuritis of the cauda equina, a chronic idiopathic polyradiculoneuritis in the horse

J F Cummings, A de Lahunta, J F Timoney

Neuritis of the cauda equina, a chronic idiopathic polyradiculoneuritis in the horse

J F Cummings et al. Acta Neuropathol. .

Abstract

Four cases of neuritis of the cauda equina (NCE) were studied by light and electron microscopy. Examination of sacral intradural rootlets revealed inflammatory cell infiltrates and an array of myelinated fiber changes which included myelin stripping by invading mononuclear cells and macrophages, as well as splitting and vesiculation of myelin lamellae without obvious participation by leukocytes. More distally in the extradural roots, there was marked granulomatous inflammation, and demyelinative changes were overshadowed by widespread evidence of irreversible axon damage. In all cases, unusual crystalline inclusions appeared in the endoneurium and sheaths of the rootlets and fascicles. The changes in NCE were compared and contrasted with those observed in acute and chronic inflammatory demyelinative neuropathies.

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References

    1. Lab Invest. 1969 Feb;20(2):127-38 - PubMed
    1. J Am Vet Med Assoc. 1970 Feb 15;156(4):478-87 - PubMed
    1. Acta Neuropathol. 1974;30(4):329-37 - PubMed
    1. J Neuropathol Exp Neurol. 1971 Apr;30(2):249-65 - PubMed
    1. Arch Pathol. 1972 Jun;93(6):552-5 - PubMed

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