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. 1990 Jul;19(4):439-42.

A study of non-toxic goitre

K W Wang  1 , C F Sum, K T Tan, W Y Ng, J S Cheah
Affiliations
  • PMID: 2221798

A study of non-toxic goitre

K W Wang et al. Ann Acad Med Singap. 1990 Jul.

Abstract

A population study showed a prevalence of 2.8% for nontoxic goitres. The clinical significance of non-toxic goitres were not previously defined. This study examined 64 patients with non-toxic goitres which were classified clinically as diffuse (gp1), lobular (gp2) and nodular (gp3). They were studied in terms of thyroid antibodies, radioisotope scanning, ultrasonography and fine-needle aspiration cytology. The goitres were mainly nodular (69%), the rest were diffuse and lobular in equal numbers. Seventy percent of the nodular goitres had 1 nodule. One case of diffuse goitre and half the lobular goitres had multinodularity demonstrated on imaging. Antithyroid antibodies were detected in 20% of gp2, 7% of gp3 and none in gp1. Malignancy was found in 2% of gp2, 11% of gp3 and nil in gp1. A management strategy for non-toxic goitre was discussed.

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