Finding the missing links in EGFR

Comment

Nicholas J Bessman et al. Nat Struct Mol Biol. 2012.

. 2012 Jan 5;19(1):1-3.

doi: 10.1038/nsmb.2221.

No abstract available

Comment on

Simultaneous visualization of the extracellular and cytoplasmic domains of the epidermal growth factor receptor.
Mi LZ, Lu C, Li Z, Nishida N, Walz T, Springer TA. Mi LZ, et al. Nat Struct Mol Biol. 2011 Aug 7;18(9):984-9. doi: 10.1038/nsmb.2092. Nat Struct Mol Biol. 2011. PMID: 21822280 Free PMC article.
ErbB1 dimerization is promoted by domain co-confinement and stabilized by ligand binding.
Low-Nam ST, Lidke KA, Cutler PJ, Roovers RC, van Bergen en Henegouwen PM, Wilson BS, Lidke DS. Low-Nam ST, et al. Nat Struct Mol Biol. 2011 Oct 23;18(11):1244-9. doi: 10.1038/nsmb.2135. Nat Struct Mol Biol. 2011. PMID: 22020299 Free PMC article.
Mechanistic insights into the activation of oncogenic forms of EGF receptor.
Wang Z, Longo PA, Tarrant MK, Kim K, Head S, Leahy DJ, Cole PA. Wang Z, et al. Nat Struct Mol Biol. 2011 Nov 20;18(12):1388-93. doi: 10.1038/nsmb.2168. Nat Struct Mol Biol. 2011. PMID: 22101934 Free PMC article.