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. 2012 Jan;27(1):46-51.
doi: 10.3346/jkms.2012.27.1.46. Epub 2011 Dec 19.

Nodal stations and diagnostic performances of endobronchial ultrasound-guided transbronchial needle aspiration in patients with non-small cell lung cancer

Byung Woo Jhun  1 , Hye Yun Park, Kyeongman Jeon, Won-Jung Koh, Gee Young Suh, Man Pyo Chung, Hojoong Kim, O Jung Kwon, Joungho Han, Sang-Won Um
Affiliations

Nodal stations and diagnostic performances of endobronchial ultrasound-guided transbronchial needle aspiration in patients with non-small cell lung cancer

Byung Woo Jhun et al. J Korean Med Sci. 2012 Jan.

Abstract

There are no accurate data on the relationship between nodal station and diagnostic performance of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). We evaluated the impact of nodal station and size on the diagnostic performance of EBUS-TBNA in patients with non-small cell lung cancer (NSCLC). Consecutive patients who underwent EBUS-TBNA of mediastinal or hilar lymph nodes for staging or diagnosis of NSCLC were included in this retrospective study. Between May 2009 and February 2010, EBUS-TBNA was performed in 373 mediastinal and hilar lymph nodes in 151 patients. The overall diagnostic sensitivity, specificity, accuracy and negative predictive value (NPV) of EBUS-TBNA were 91.6%, 98.6%, 93.8%, and 84.3%, respectively. NPV of the left side nodal group was significantly lower than those of the other groups (P = 0.047) and sensitivity of the left side nodal group tended to decrease (P = 0.096) compared with those of the other groups. Diagnostic sensitivity and NPV of 4L lymph node were 83.3% and 66.7%, respectively. However, diagnostic performances of EBUS-TBNA did not differ according to nodal size. Bronchoscopists should consider the impact of nodal stations on diagnostic performances of EBUS-TBNA.

Keywords: Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration; Lymph Nodes; Mediastinum; Non-Small Cell Lung Cancer.

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Figures

Fig. 1
Fig. 1
Results of lymph nodes sampled by EBUS-TBNA. LN, lymph node; EBUS-TBNA, endobronchial ultrasound-guided transbronchial needle aspiration; CCRT, concurrent chemoradiotherapy.
See this image and copyright information in PMC

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