Irreversible inhibitors of tissue transglutaminase
- PMID: 22220480
- DOI: 10.1002/9781118105771.ch10
Irreversible inhibitors of tissue transglutaminase
Similar articles
-
Dihydroisoxazole analogs for labeling and visualization of catalytically active transglutaminase 2.Chem Biol. 2011 Jan 28;18(1):58-66. doi: 10.1016/j.chembiol.2010.11.004. Chem Biol. 2011. PMID: 21276939 Free PMC article.
-
Potent transglutaminase inhibitors, dithio β-aminoethyl ketones.Bioorg Med Chem Lett. 2011 Jan 1;21(1):377-9. doi: 10.1016/j.bmcl.2010.10.136. Epub 2010 Oct 31. Bioorg Med Chem Lett. 2011. PMID: 21134746
-
Discovery of potent and specific dihydroisoxazole inhibitors of human transglutaminase 2.J Med Chem. 2014 Nov 13;57(21):9042-64. doi: 10.1021/jm501145a. Epub 2014 Oct 31. J Med Chem. 2014. PMID: 25333388 Free PMC article.
-
Recent Progress in the Development of Transglutaminase 2 (TGase2) Inhibitors.J Med Chem. 2017 Jan 26;60(2):554-567. doi: 10.1021/acs.jmedchem.6b01036. Epub 2016 Nov 21. J Med Chem. 2017. PMID: 28122456 Review.
-
Transglutaminase as a therapeutic target for celiac disease.Expert Opin Ther Targets. 2015 Mar;19(3):335-48. doi: 10.1517/14728222.2014.985207. Epub 2014 Nov 20. Expert Opin Ther Targets. 2015. PMID: 25410283 Review.
Cited by
-
Irreversible 4-Aminopiperidine Transglutaminase 2 Inhibitors for Huntington's Disease.ACS Med Chem Lett. 2012 Aug 9;3(9):731-5. doi: 10.1021/ml3001352. eCollection 2012 Sep 13. ACS Med Chem Lett. 2012. PMID: 24900540 Free PMC article.
-
Sulforaphane covalently interacts with the transglutaminase 2 cancer maintenance protein to alter its structure and suppress its activity.Mol Carcinog. 2022 Jan;61(1):19-32. doi: 10.1002/mc.23356. Epub 2021 Oct 5. Mol Carcinog. 2022. PMID: 34610184 Free PMC article.
-
Structure-Activity Relationships of Potent, Targeted Covalent Inhibitors That Abolish Both the Transamidation and GTP Binding Activities of Human Tissue Transglutaminase.J Med Chem. 2017 Sep 28;60(18):7910-7927. doi: 10.1021/acs.jmedchem.7b01070. Epub 2017 Sep 14. J Med Chem. 2017. PMID: 28858494 Free PMC article.
-
Transglutaminase 2 function in glioblastoma tumor efferocytosis.Cell Death Dis. 2025 Jul 3;16(1):487. doi: 10.1038/s41419-025-07819-2. Cell Death Dis. 2025. PMID: 40610434 Free PMC article.
-
In silico studies of the open form of human tissue transglutaminase.Sci Rep. 2024 Jul 10;14(1):15981. doi: 10.1038/s41598-024-66348-8. Sci Rep. 2024. PMID: 38987418 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Other Literature Sources