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. 2012 Mar 12;8(5):666-70.
doi: 10.1002/smll.201102361. Epub 2012 Jan 5.

Self-fluorescence of chemically crosslinked MRI nanoprobes to enable multimodal imaging of therapeutic cells

Hyun Min Kim  1 , Young-Woock Noh, Hye Sun Park, Mi Young Cho, Kwan Soo Hong, Hyunseung Lee, Da Hye Shin, Jongeun Kang, Moon-Hee Sung, Haryoung Poo, Yong Taik Lim
Affiliations

Self-fluorescence of chemically crosslinked MRI nanoprobes to enable multimodal imaging of therapeutic cells

Hyun Min Kim et al. Small. .

Abstract

Old chemistry for novel materials: Self-fluorescent high-relaxivity T(2)-weighted magnetic resonance imaging (MRI) contrast agents are produced. They are a novel type of MR/optical dual-modality in vivo imaging nanoprobe using glutaraldehyde crosslinking chemistry, and they are used to label and monitor therapeutic cells both in vitro and in vivo.

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