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Randomized Controlled Trial
. 2012 Jan 6:13:4.
doi: 10.1186/1745-6215-13-4.

A cost-effectiveness analysis of provider interventions to improve health worker practice in providing treatment for uncomplicated malaria in Cameroon: a study protocol for a randomized controlled trial

Affiliations
Randomized Controlled Trial

A cost-effectiveness analysis of provider interventions to improve health worker practice in providing treatment for uncomplicated malaria in Cameroon: a study protocol for a randomized controlled trial

Virginia Wiseman et al. Trials. .

Abstract

Background: Governments and donors all over Africa are searching for sustainable, affordable and cost-effective ways to improve the quality of malaria case management. Widespread deficiencies have been reported in the prescribing and counselling practices of health care providers treating febrile patients in both public and private health facilities. Cameroon is no exception with low levels of adherence to national guidelines, the frequent selection of non-recommended antimalarials and the use of incorrect dosages. This study evaluates the effectiveness and cost-effectiveness of introducing two different provider training packages, alongside rapid diagnostic tests (RDTs), designed to equip providers with the knowledge and practical skills needed to effectively diagnose and treat febrile patients. The overall aim is to target antimalarial treatment better and to facilitate optimal use of malaria treatment guidelines.

Methods/design: A 3-arm stratified, cluster randomized trial will be conducted to assess whether introducing RDTs with provider training (basic or enhanced) is more cost-effective than current practice without RDTs, and whether there is a difference in the cost effectiveness of the provider training interventions. The primary outcome is the proportion of patients attending facilities that report a fever or suspected malaria and receive treatment according to malaria guidelines. This will be measured by surveying patients (or caregivers) as they exit public and mission health facilities. Cost-effectiveness will be presented in terms of the primary outcome and a range of secondary outcomes, including changes in provider knowledge. Costs will be estimated from a societal and provider perspective using standard economic evaluation methodologies.

Trial registration: ClinicalTrials.gov: NCT00981877.

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Figures

Figure 1
Figure 1
Effect of Provider Interventions on the Treatment Received by Patients.
Figure 2
Figure 2
Primary outcome measure.
Figure 3
Figure 3
Eligibility, selection, enrolment and methods of data collection.

References

    1. Nshakira N, Kristensen M, Ssali F, Whyte SR. Appropriate treatment of malaria? Use of antimalarial drugs for children's fevers in district medical units, drug shops and homes in eastern Uganda. Trop Med Int Health. 2002;7:309–316. doi: 10.1046/j.1365-3156.2002.00858.x. - DOI - PubMed
    1. Williams H, Jones C. A critical review of behavioral issues related to malaria control in sub-Saharan Africa: what contributions have social scientists made? Soc Sci & Med. 2004;59:501–523. doi: 10.1016/j.socscimed.2003.11.010. - DOI - PubMed
    1. Reyburn H, Mbakilwa H, Mwangi R, Obeni M, Raimos O. Rapid diagnostic tests compared with malaria microscopy for guiding outpatient treatment of febrile illness in Tanzania: randomized trial. BMJ. 2007;334:403. doi: 10.1136/bmj.39073.496829.AE. - DOI - PMC - PubMed
    1. Zurovac D, Njogu J, Akhwale W, Hamer DH, Snow RW. Translation of artemether-lumefantrine treatment policy into paediatric clinical practice: an early experience from Kenya. Trop Med Int Health. 2008;13:99–107. doi: 10.1111/j.1365-3156.2007.01980.x. - DOI - PMC - PubMed
    1. Zurovac D, Tibenderana JK, Nankabirwa J, Ssekitooleko J, Njogu JN, Rwakimari JB, Meek S, Talisuna A, Snow RW. Malaria case-management under artemether-lumefantrine treatment policy in Uganda. Malar J. 2008;7:181. doi: 10.1186/1475-2875-7-181. - DOI - PMC - PubMed

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