Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2012 Jan 4;15(1):8-9.
doi: 10.1016/j.cmet.2011.12.004.

IL-6 muscles in on the gut and pancreas to enhance insulin secretion

Tamara L Allen  1 , Martin Whitham, Mark A Febbraio
Affiliations
Free article
Comment

IL-6 muscles in on the gut and pancreas to enhance insulin secretion

Tamara L Allen et al. Cell Metab. .
Free article

Abstract

The role of the cytokine interleukin-6 (IL-6) in metabolic homeostasis is the subject of conjecture. Recent work in Nature Medicine (Ellingsgaard et al., 2011) demonstrates that IL-6 released from skeletal muscle during exercise mediates crosstalk between insulin-sensitive tissues, intestinal L cells, and pancreatic islets to adapt to changes in insulin demand.

PubMed Disclaimer

Comment on

LinkOut - more resources