doi: 10.1039/c2cc16758a.
Epub 2012 Jan 9.
Synthesis of α-indanones via intramolecular direct arylation with cyclopropanol-derived homoenolates
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- PMID: 22227533
- DOI: 10.1039/c2cc16758a
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Synthesis of α-indanones via intramolecular direct arylation with cyclopropanol-derived homoenolates
Chem Commun (Camb).
.
Abstract
A palladium-catalysed, tandem cyclopropanol rearrangement and direct arylation approach for the synthesis of 1-indanones is reported. The reaction is generally high yielding, uses oxygen as the terminal oxidant and tolerates a range of functional groups on the aryl ring.
This journal is © The Royal Society of Chemistry 2012
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