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. 2011;8(2):128-33.
doi: 10.4314/ajtcam.v8i2.63198. Epub 2010 Dec 30.

The effects of Taraxacum officinale extracts (TOE) supplementation on physical fatigue in mice

Zhang Jinchun  1 , Chen Jie
Affiliations

The effects of Taraxacum officinale extracts (TOE) supplementation on physical fatigue in mice

Zhang Jinchun et al. Afr J Tradit Complement Altern Med. 2011.

Abstract

The study is to investigate the effect of Taraxacum officinale extracts (TOE) supplementation on physical fatigue based on the forced swimming capacity in mice. Forty Kunming male mice were randomly divided into 4 groups, i.e., normal control (NC) and three doses of TOE treated group (High-dose, Middle-dose and Low-dose). Three TOE treated groups were treated by oral TOE with 10, 30 and 100mg/kg b.w respectively for a period of 42 days. The normal control group was given a corresponding volume of sterile distilled water. After 6 weeks, the forced swimming capacity and blood biochemical parameters in mice were measured, and the result showed that TOE had an anti- physical fatigue effect. It enhanced the maximum swimming capacity of mice, effectively delayed the lowering of glucose in the blood, and prevented the increase in lactate and triglyceride concentrations.

Keywords: Taraxacum officinale extracts; forced swimming capacity; mice.

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Figures

Figure 1
Figure 1
Effect of TOE on the body weight of mice. Each value represents mean ± SD; n = 10.
Figure 2
Figure 2
Effect of TOE on the forced swimming capacity in mice Each value represents mean ± SD; n = 10. a p < 0.05, compared with normal control group.
See this image and copyright information in PMC

References

    1. Abe T, Takiguchi Y, Tamura M, Shimura J, Yamazaki KI. Effect of vespa amino acid mixture (VAAM) isolated from hornet larval saliva and modified VMM nutrients on endurance exercise in swimming mice improvement in performance and changes of blood lactate and glucose. Jpn J Physiol Fitness Sports Med. 1995;44:225–238.
    1. Babcock MA, Johnson BD, Pegelow DF, Suman OE, Griffin D, Dempsey JA. Hypoxic effects on exercise-induced diaphragmatic fatigue in normal healthy humans. J Appl Physiol. 1995;78:82–92. - PubMed
    1. Borer KT, Wuorinen EC, Lukos JR, Denver JW, Porges SW, Burant CF. Two bouts of exercise before meals, but not after meals, lower fasting blood glucose. Med Sci Sports Exerc. 2009;41:1606–1614. - PubMed
    1. Cao SH, Shang HP, Wu WB, Du JR, Putheti R. Evaluation of anti-athletic fatigue activity of Schizandra chinensis aqueous extracts in mice. African Journal of Pharmacy and Pharmacology. 2009;3:593–597.
    1. Fueger PT, Li CY, Ayala JE, Shearer J, Bracy DP, Charron MJ, Rottman JN, Wasserman DH. Glucose kinetics and exercise tolerance in mice lacking the GLUT4 glucose transporter. J Physiol. 2007;582:801–812. - PMC - PubMed

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