Review
[The effect of translation inhibitor cycloheximide on expression of mammalian genes]
[Article in
Russian]
- PMID: 2223902
Item in Clipboard
Review
[The effect of translation inhibitor cycloheximide on expression of mammalian genes]
[Article in
Russian]
Biokhimiia.
1990 Jul.
Abstract
The data concerning the cycloheximide influence on individual mRNA content, transcription rate and chromatin structure in mammalian cells are reviewed. The putative mechanism of cycloheximide effect is explained as being due to the existence of short-living regulatory proteins. It is concluded that cycloheximide is a helpful tool in the study of regulation of gene expression in mammalian cells.
Similar articles
-
Transcriptional regulation of secretogranin II and chromogranin B by cyclic AMP in a rat pheochromocytoma cell line.Mol Pharmacol. 1994 Nov;46(5):880-9. Mol Pharmacol. 1994. PMID: 7969075
-
Protein synthesis inhibitors cycloheximide and anisomycin induce interleukin-6 gene expression and activate transcription factor NF-kappaB.Biochem Biophys Res Commun. 1997 Apr 17;233(2):507-13. doi: 10.1006/bbrc.1997.6489. Biochem Biophys Res Commun. 1997. PMID: 9144567
-
Cycloheximide inhibition of delayed early gene expression in baculovirus-infected cells.Virology. 1997 May 26;232(1):105-13. doi: 10.1006/viro.1997.8557. Virology. 1997. PMID: 9185594
-
Effect of TPA on aquaporin 4 mRNA expression in cultured rat astrocytes.Glia. 1999 Feb 1;25(3):240-6. Glia. 1999. PMID: 9932870
-
Posttranscriptional regulation of osteocalcin mRNA in clonal osteoblast cells by 1,25-dihydroxyvitamin D3.Arch Biochem Biophys. 1996 Aug 1;332(1):142-52. doi: 10.1006/abbi.1996.0326. Arch Biochem Biophys. 1996. PMID: 8806719
Cited by
-
The angiogenic factor Cyr61 is induced by the progestin R5020 and is necessary for mammary adenocarcinoma cell growth.Endocrine. 2002 Jul;18(2):147-59. doi: 10.1385/ENDO:18:2:147. Endocrine. 2002. PMID: 12374462
-
S-phase-dependent action of cycloheximide in relieving chromatin-mediated general transcriptional repression.Biochem J. 1998 Dec 15;336 ( Pt 3)(Pt 3):619-24. doi: 10.1042/bj3360619. Biochem J. 1998. PMID: 9841873 Free PMC article.
-
Cell adhesion promotes Ebola virus envelope glycoprotein-mediated binding and infection.J Virol. 2008 Jul;82(14):7238-42. doi: 10.1128/JVI.00425-08. Epub 2008 Apr 30. J Virol. 2008. PMID: 18448524 Free PMC article.
-
SYVN1-MTR4-MAT2A Signaling Axis Regulates Methionine Metabolism in Glioma Cells.Front Cell Dev Biol. 2021 Mar 30;9:633259. doi: 10.3389/fcell.2021.633259. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 33859984 Free PMC article.