Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2011 Dec;76(6):528-30.
doi: 10.1016/j.wneu.2011.06.053.

Surgery for glioblastoma multiforme: striking a balance

Affiliations
Comment

Surgery for glioblastoma multiforme: striking a balance

Raymund L Yong et al. World Neurosurg. 2011 Dec.
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Conceptual framework for the relationship between risk and benefit for cytoreductive glioblastoma surgery according to tumor resectability and preoperative prognosis. Black curves indicate expected average months of survival gained from tumor cytoreduction if the extent of resection (EOR) threshold is assumed to be approximately 80%. Red curves indicate expected average months of survival lost due to general perioperative complications and surgically acquired neurological deficits. Shaded area indicates the range of EOR within which a net survival benefit exists. Arrows indicate EOR at which benefit is maximal for each scenario. Question marks indicate scenarios where projected net benefit may not be clinically meaningful.

Comment on

References

    1. Brown PD, Ballman KV, Rummans TA, Maurer MJ, Sloan JA, Boeve BF, Gupta L, Tang-Wai DF, Arusell RM, Clark MM, Buckner JC. Prospective study of quality of life in adults with newly diagnosed high-grade gliomas. J Neurooncol. 2006;76:283–291. - PubMed
    1. Chaichana KL, Halthore AN, Parker SL, Olivi A, Weingart JD, Brem H, Quinones-Hinojosa A. Factors involved in maintaining prolonged functional independence following supratentorial glioblastoma resection. Clinical article. J Neurosurg. 2011;114:604–612. - PMC - PubMed
    1. Ciric I, Ammirati M, Vick N, Mikhael M. Supratentorial gliomas: surgical considerations and immediate postoperative results. Gross total resection versus partial resection. Neurosurgery. 1987;21:21–26. - PubMed
    1. Fadul C, Wood J, Thaler H, Galicich J, Patterson RH, Jr, Posner JB. Morbidity and mortality of craniotomy for excision of supratentorial gliomas. Neurology. 1988;38:1374–1379. - PubMed
    1. Lacroix M, Abi-Said D, Fourney DR, Gokaslan ZL, Shi W, DeMonte F, Lang FF, McCutcheon IE, Hassenbusch SJ, Holland E, Hess K, Michael C, Miller D, Sawaya R. A multivariate analysis of 416 patients with glioblastoma multiforme: prognosis, extent of resection, and survival. J Neurosurg. 2001;95:190–198. - PubMed