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Review
. 2010 Mar;2(3):389-407.
doi: 10.3390/nu2030389. Epub 2010 Mar 23.

Vitamin D status during pregnancy and aspects of offspring health

Anne-Louise Ponsonby  1 , Robyn M Lucas, Sharon Lewis, Jane Halliday
Affiliations
Review

Vitamin D status during pregnancy and aspects of offspring health

Anne-Louise Ponsonby et al. Nutrients. 2010 Mar.

Abstract

Low maternal vitamin D levels during pregnancy have been linked to various health outcomes in the offspring, ranging from periconceptional effects to diseases of adult onset. Maternal and infant cord 25(OH)D levels are highly correlated. Here, we review the available evidence for these adverse health effects. Most of the evidence has arisen from observational epidemiological studies, but randomized controlled trials are now underway. The evidence to date supports that women should be monitored and treated for vitamin D deficiency during pregnancy but optimal and upper limit serum 25(OH)D levels during pregnancy are not known.

Keywords: offspring health; pregnancy; sun exposure; ultraviolet radiation; vitamin D.

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Figures

Figure 1
Figure 1
Manifestation of reviewed possible major outcomes related to vitamin D status at different life stages.
See this image and copyright information in PMC

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