Royal Free Hospital protocol for 24-hour intragastric acidity and plasma gastrin concentration
- PMID: 2225513
- DOI: 10.1159/000171287
Royal Free Hospital protocol for 24-hour intragastric acidity and plasma gastrin concentration
Abstract
The Royal Free Hospital protocol for simultaneous measurement of 24-hour intragastric acidity and plasma gastrin concentration is described in detail. The methods of analysing such data are discussed, with recommendations for a standard four-way analysis: median hourly 24-hour intragastric acidity or pH, or plasma gastrin concentration; integrated 24-hour intragastric acidity, or plasma gastrin concentration; analysis of integrated values according to meal-related intervals; and quantification of the percentage of time in a 24-hour period that intragastric pH is greater than 3.
Similar articles
-
Gastric aspiration technique for pH recording: a critical evaluation of this method.Dig Dis. 1990;8 Suppl 1:3-9. doi: 10.1159/000171273. Dig Dis. 1990. PMID: 2225516
-
A placebo-controlled study to assess the effects of 7-day dosing with 10, 20 and 40 mg rabeprazole on 24-h intragastric acidity and plasma gastrin in healthy male subjects.Aliment Pharmacol Ther. 2000 Jun;14(6):691-9. doi: 10.1046/j.1365-2036.2000.00772.x. Aliment Pharmacol Ther. 2000. PMID: 10848651 Clinical Trial.
-
Twenty-four-hour intragastric acidity and plasma gastrin concentration before and during treatment with either ranitidine or omeprazole.Aliment Pharmacol Ther. 1987 Jun;1(3):239-51. doi: 10.1111/j.1365-2036.1987.tb00623.x. Aliment Pharmacol Ther. 1987. PMID: 2979226
-
Cholecystokinin in the control of gastric acid and plasma gastrin and somatostatin secretion in healthy subjects and duodenal ulcer patients before and after eradication of Helicobacter pylori.J Physiol Pharmacol. 1994 Dec;45(4 Suppl 1):3-66. J Physiol Pharmacol. 1994. PMID: 7787215 Review.
-
Drug-induced changes of plasma gastrin concentration.Gastroenterol Clin North Am. 1990 Mar;19(1):141-53. Gastroenterol Clin North Am. 1990. PMID: 2184125 Review.
Cited by
-
Decrease of intragastric acidity in healthy subjects dosed with ranitidine 75 mg, cimetidine 200 mg, or placebo.Dig Dis Sci. 2002 Jan;47(1):54-7. doi: 10.1023/a:1013255201858. Dig Dis Sci. 2002. PMID: 11837732 Clinical Trial.
-
Effects of ranitidine 150 mg four times a day on 24-hour intragastric acidity and 24-hour plasma gastrin concentration.Dig Dis Sci. 1994 Jan;39(1):91-6. doi: 10.1007/BF02090066. Dig Dis Sci. 1994. PMID: 8281874 Clinical Trial.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources