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. 2011:2011:7965-8.
doi: 10.1109/IEMBS.2011.6091964.

Classification of astrocytomas and oligodendrogliomas from mass spectrometry data using sparse kernel machines

Jacob Huang  1 , Behnood Gholami, Nathalie Y R Agar, Isaiah Norton, Wassim M Haddad, Allen R Tannenbaum
Affiliations

Classification of astrocytomas and oligodendrogliomas from mass spectrometry data using sparse kernel machines

Jacob Huang et al. Annu Int Conf IEEE Eng Med Biol Soc. 2011.

Abstract

Glioma histologies are the primary factor in prognostic estimates and are used in determining the proper course of treatment. Furthermore, due to the sensitivity of cranial environments, real-time tumor-cell classification and boundary detection can aid in the precision and completeness of tumor resection. A recent improvement to mass spectrometry known as desorption electrospray ionization operates in an ambient environment without the application of a preparation compound. This allows for a real-time acquisition of mass spectra during surgeries and other live operations. In this paper, we present a framework using sparse kernel machines to determine a glioma sample's histopathological subtype by analyzing its chemical composition acquired by desorption electrospray ionization mass spectrometry.

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References

    1. Jemal A, Siegel R, Xu J, Ward E. Cancer Statistics, 2010. Cancer J. Clin. 2010 Jul; http://caonline.amcancersoc.org/
    1. Altekruse SF, Kosary CL, Krapcho M, Neyman N, Aminou R, Waldron W, Ruhl J, Howlader N, Tatalovich Z, Cho H, Mariotto A, Eisner MP, Lewis DR, Cronin K, Chen HS, Feuer EJ, Stinchcomb DG, Edwards BK. SEER Cancer Statistics Review 1975-2007. Bethesda, MD: http://www.seer.cancer.gov/csr/1975_2007/
    1. American Cancer Society . Brain and Spinal Cord Tumors in Adults. Atlanta, GA: 2009. http://www.cancer.org/cancer/braincnstumorsinadults/
    1. Edge SB, Byrd DR. AJCC Cancer Staging Manual. 7th ed. Springer-Verlag; New York, NY: 2009.
    1. Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, Scheithauer BW, Kleihues P. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathologica. 2007 Aug;114(2):97–109. - PMC - PubMed

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