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Case Reports
. 2012 Jan;18(1):102-4.
doi: 10.3201/eid1801.110471.

Asymmetric type F botulism with cranial nerve demyelination

Alina Filozov  1 , Jessica A Kattan, Lavanya Jitendranath, C Gregory Smith, Carolina Lúquez, Quyen N Phan, Ryan P Fagan
Affiliations
Case Reports

Asymmetric type F botulism with cranial nerve demyelination

Alina Filozov et al. Emerg Infect Dis. 2012 Jan.

Abstract

We report a case of type F botulism in a patient with bilateral but asymmetric neurologic deficits. Cranial nerve demyelination was found during autopsy. Bilateral, asymmetric clinical signs, although rare, do not rule out botulism. Demyelination of cranial nerves might be underrecognized during autopsy of botulism patients.

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Figures

Figure
Figure
Postmortem cranial nerve tissue from a patient with botulism. A) Fragmentation of myelin sheaths and inflammatory infiltration of B and CD3+ T-cells within the nerve tissue (original magnification ×200). B) B-cell infiltration of nerve tissue; C) CD68-positive myelinoklastic macrophages (original magnification ×400).
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