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Review
. 2012 Sep;83(3):422-31.
doi: 10.1016/j.critrevonc.2011.12.004. Epub 2012 Jan 17.

Target therapy in elderly breast cancer patients

Paolo Carli  1 , Elisa Turchet, Daniela Quitadamo, Antonella Spada, Gianmaria Miolo, Elda Lamaj, Simon Spazzapan, Vincenzo Di Lauro, Riccardo Dolcetti, Andrea Veronesi, Diana Crivellari
Affiliations
Review

Target therapy in elderly breast cancer patients

Paolo Carli et al. Crit Rev Oncol Hematol. 2012 Sep.

Abstract

Substantial progress has been made in the management of breast cancer by targeting HER2 and VEGF pathways. Although the efficacy and safety of target therapy in breast cancer have been established, no specific phase III trial has addressed these issues in the elderly population and the only data available derive from subanalyses or retrospective series. The aim of this review is to summarize the available evidence in this special population and to encourage further well designed studies in elderly breast cancer patients.

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