Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2012 Jan 18:4:2.
doi: 10.1186/1758-3284-4-2.

Randomized clinical trial of LigaSure versus conventional suture ligation in thyroid surgery

Anandi H W Schiphorst  1 , Bas A Twigt, Sjoerd G Elias, Thijs van Dalen
Affiliations
Randomized Controlled Trial

Randomized clinical trial of LigaSure versus conventional suture ligation in thyroid surgery

Anandi H W Schiphorst et al. Head Neck Oncol. .

Expression of concern in

  • Comment: Head and Neck Oncology.
    BioMed Central. BioMed Central. BMC Med. 2014 Feb 5;12:24. doi: 10.1186/1741-7015-12-24. BMC Med. 2014. PMID: 24499430 Free PMC article. Review.

Abstract

Background: In thyroid surgery vessel division and haemostasis make up an important and time consuming part of the operation. While the presence of the recurrent laryngeal nerve limits the liberal use of diathermia, the many arterial and venous branches to and from the thyroid gland necessitates the use of numerous conventional suture ligatures.This study evaluates the effect of using a vessel sealing system on operation time during thyroid surgery.

Methods: A randomized clinical trial was performed between September 2005 and October 2008 in a teaching hospital. Forty patients undergoing total hemithyroidectomy participated in the trial. Twenty were randomized to the intraoperative use of the LigaSure Precise™ vessel sealing system, and twenty to the use of conventional suture ligatures.

Results: The total median operation time was 10 minutes shorter in the LigaSure group (56 versus 66 minutes, P = 0.001). No significant differences in complications were noticed.

Conclusion: Using an electrothermal vessel sealing system during thyroid surgery is time saving.

Trial registration: This trial was registered in the international standard randomized controlled trials number register (ISRCTNR) under number ISRCTNR82389535.

PubMed Disclaimer

Figures

Figure 1
Figure 1
CONSORT diagram template.
Figure 2
Figure 2
Forest plot of randomized trials measuring operative time in thyroid surgery (Ligasure versus conventional suture ligations).
See this image and copyright information in PMC

References

    1. Lee WJ, Chen TC, Lai IR, Wang W, Huang MT. Randomized clinical trial of Ligasure versus conventional surgery for extended gastric cancer resection. Br J Surg. 2003;90(12):1493–6. doi: 10.1002/bjs.4362. - DOI - PubMed
    1. Muzi MG, Milito G, Nigro C, Cadeddu F, Andreoli F, Amabile D, Farinon AM. Randomized clinical trial of LigaSure and conventional diathermy haemorrhoidectomy. Br J Surg. 2007;94:937–942. doi: 10.1002/bjs.5904. - DOI - PubMed
    1. Saiura A, Yamamoto J, Koga R, Sakamoto Y, Kokudo N, Seki M, Yamaguchi T, Yamaguchi T, Muto T, Makuuchi M. Usefulness of LigaSure for liver resection: analysis by randomized clinical trial. Am J Surg. 2006;192:41–45. doi: 10.1016/j.amjsurg.2006.01.025. - DOI - PubMed
    1. Manouras A, Lagoudianakis EE, Antonakis PT, Filippakis GM, Markogiannakis H, Kekis PB. Electrothermal bipolar vessel sealing system is a safe and time-saving alternative to classic suture ligation in total thyroidectomy. Head Neck. 2005;27:959–962. doi: 10.1002/hed.20271. - DOI - PubMed
    1. Saint Marc O, Cogliandolo A, Piquard A, Famà F, Pidoto RR. LigaSure vs clamp-and-tie technique to achieve hemostasis in total thyroidectomy for benign multinodular goiter: a prospective randomized study. Arch Surg. 2007;142:150–156. doi: 10.1001/archsurg.142.2.150. discussion 157. - DOI - PubMed

Publication types

Associated data

LinkOut - more resources