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. 2012:737:169-74.
doi: 10.1007/978-1-4614-1566-4_25.

3-D high-resolution mapping of the heterogeneity in mitochondrial redox state of human breast tumor xenografts

H N Xu  1 , S Nioka, B Chance, L Z Li
Affiliations

3-D high-resolution mapping of the heterogeneity in mitochondrial redox state of human breast tumor xenografts

H N Xu et al. Adv Exp Med Biol. 2012.
No abstract available

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Figures

Fig. 25.1
Fig. 25.1
Typical images of redox scanning of the mouse xenografts of MCF-7 (top two rows, d = 1,400 μm); MDA-MB-468 (middle two rows, d = 1,400 μm); MDA-MB-231 (bottom two rows, d = 3,600 μm) tumor lines. The Fp or NADH redox ratio ranges between 0 and 1; the Fp or NADH images are in the unit of μM in reference to the corresponding standards. The x-axes of the corresponding histograms represent the Fp redox ratio or concentration. The y-axes represent the number of pixels in the tumor sections having a specific value of Fp redox ratio or concentration. The small round spots outside the tumor sections are the images of Fp or NADH reference standards. The image matrix was 64 × 64 with a resolution of 200 μm
Fig. 25.2
Fig. 25.2
Depth-dependent redox indices. The Fp redox ratios (a–c) and the Fp and NADH nominal concentrations in μM (d–e) at different depths of the three tumors: MCF-7, MDA-MB-468, and MDA-MB-231
See this image and copyright information in PMC

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