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. 2012 Jan 18;4(117):117fs2.
doi: 10.1126/scitranslmed.3003385.

Immunology taught by humans

Affiliations

Immunology taught by humans

Mark M Davis. Sci Transl Med. .

Abstract

After a half-century of mouse-dominated research, human immunology is making a comeback. Informed by mouse studies and powered by new techniques, human immune research is both advancing disease treatment and providing new insights into basic biology.

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Figures

Fig. 1
Fig. 1. Travel advisory
TCM cells leave the skin and enter the circulation, making them susceptible to antibody annihilation. TEM cells stay in the skin and are protected from assault by alemtuzumab therapy . While the illustration shows only the cytotoxic T cell lineage, it is believed that helper T cells (TH) follow a similar course. TCR, T cell receptor; MHC, major histocompatibility complex.

References

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