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. 2012 Mar 7;10(9):1739-42.
doi: 10.1039/c2ob06784f. Epub 2012 Jan 20.

Unexpected enzyme-catalyzed regioselective acylation of flavonoid aglycones and rapid product screening

Eleni Kyriakou  1 , Alexandra Primikyri, Pantelis Charisiadis, Maria Katsoura, Ioannis P Gerothanassis, Haralambos Stamatis, Andreas G Tzakos
Affiliations

Unexpected enzyme-catalyzed regioselective acylation of flavonoid aglycones and rapid product screening

Eleni Kyriakou et al. Org Biomol Chem. .

Abstract

Unprecedented regioselective acylation of flavonoid aglycones was achieved using Candida antarctica lipase B (CALB). The rapid screening of product formation was performed by the use of the high resolution phenol-type OH (1)H NMR spectral region recorded after the addition of picric acid.

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