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. 2011 Apr;44(2):131-6.
doi: 10.5090/kjtcs.2011.44.2.131. Epub 2011 Apr 14.

Aortic Valve Replacement for Aortic Stenosis and Concomitant Coronary Artery Bypass: Long-term Outcomes and Predictors of Mortality

Won-Chul Cho  1 , Dong-Gon Yoo, Joon-Bum Kim, Jae-Won Lee, Suk-Jung Choo, Sung-Ho Jung, Cheol-Hyun Chung
Affiliations

Aortic Valve Replacement for Aortic Stenosis and Concomitant Coronary Artery Bypass: Long-term Outcomes and Predictors of Mortality

Won-Chul Cho et al. Korean J Thorac Cardiovasc Surg. 2011 Apr.

Abstract

Background: We evaluated the surgical results and predictors of long-term survival in patients who underwent coronary artery bypass grafting (CABG) at the time of an aortic valve replacement (AVR) due to aortic stenosis.

Materials and methods: Between January 1990 and December 2009, 183 consecutive patients underwent CABG and concomitant aortic valve replacement for aortic stenosis. The mean follow-up period was 59.8±3.3 months and follow-up was possible in 98.3% of cases. Predictors of mortality were determined by Cox regression analysis.

Results: There were 5 (2.7%) in-hospital deaths. Follow-up of the in-hospital survivors documented late survival rates of 91.5%, 74.8%, and 59.6% at 1, 5, and 10 postoperative years, respectively. Age (p<0.001), a glomerular filtration rate (GFR) less than 60 mL/min (p=0.006), and left ventricular (LV) mass (p<0.001) were significant predictors of mortality in the multivariate analysis.

Conclusion: The surgical results and long-term survival of aortic valve replacement with concomitant CABG in patients with aortic stenosis and coronary artery disease were acceptable. Age, a GFR less than 60 mL/min, and LV mass were significant predictors of mortality.

Keywords: Aortic valve stenosis; Coronary artery bypass surgery; Coronary artery disease.

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Figures

Fig. 1
Fig. 1
Long-term survival rate.
Fig. 2
Fig. 2
Freedom from Major adverse cardiac events (MACE) and mortality.
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