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Multicenter Study
. 2012;33(1):48-59.
doi: 10.1080/08897077.2011.609438.

A multisite pilot study of extended-release injectable naltrexone treatment for previously opioid-dependent parolees and probationers

Donna M Coviello  1 , James W Cornish, Kevin G Lynch, Tamara Y Boney, Cynthia A Clark, Joshua D Lee, Peter D Friedmann, Edward V Nunes, Timothy W Kinlock, Michael S Gordon, Robert P Schwartz, Elie S Nuwayser, Charles P O'Brien
Affiliations
Multicenter Study

A multisite pilot study of extended-release injectable naltrexone treatment for previously opioid-dependent parolees and probationers

Donna M Coviello et al. Subst Abus. 2012.

Abstract

A feasibility study was conducted to pilot test the ability of 5 sites to recruit, treat, and retain opioid-dependent offenders in a trial of extended-release injectable naltrexone (XR-NTX). The participants, 61 previously opioid-dependent individuals under legal supervision in the community, received up to 6 monthly injections of Depotrex brand naltrexone and completed a 6-month follow-up interview. Six-month outcomes showed that those who completed treatment had significantly fewer opioid-positive urines and were less likely to have been incarcerated than those who had not completed treatment. The findings indicate that XR-NTX holds promise as a feasible, effective treatment option for opioid-dependent offenders.

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