Stroke. Geometry is destiny for carotid atherosclerotic plaques
- PMID: 22270018
- DOI: 10.1038/nrneurol.2012.1
Stroke. Geometry is destiny for carotid atherosclerotic plaques
Abstract
The geometry of carotid arteries, both normal and narrowed, produces flow characteristics that predict the location of atherosclerosis and the site of plaque rupture. A recent study has shown that the upstream carotid plaque undergoes profound biochemical and apoptotic changes that are closely linked to the development of stroke symptoms.
Comment on
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Carotid plaque vulnerability: a positive feedback between hemodynamic and biochemical mechanisms.Stroke. 2011 Dec;42(12):3502-10. doi: 10.1161/STROKEAHA.111.627265. Epub 2011 Oct 13. Stroke. 2011. PMID: 21998063
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