Conjugal amyotrophic lateral sclerosis
- PMID: 22275781
- PMCID: PMC3246851
- DOI: 10.1080/08998280.2012.11928778
Conjugal amyotrophic lateral sclerosis
Abstract
Amyotrophic lateral sclerosis (ALS) is a disease characterized by progressive degeneration of motor neurons in the motor cortex, brainstem, and spinal cord. The incidence of sporadic ALS is 1.5 to 2.7 in 100,000, and the prevalence is 5.2 to 6.0 in 100,000. Conjugal ALS is even rarer than sporadic ALS. We report a case of conjugal ALS encountered in our outpatient neurology clinic.
Similar articles
-
β-N-methylamino-l-alanine causes neurological and pathological phenotypes mimicking Amyotrophic Lateral Sclerosis (ALS): the first step towards an experimental model for sporadic ALS.Environ Toxicol Pharmacol. 2013 Sep;36(2):243-255. doi: 10.1016/j.etap.2013.04.007. Epub 2013 Apr 25. Environ Toxicol Pharmacol. 2013. PMID: 23688553
-
Sporadic amyotrophic lateral sclerosis: is SMN-Gemins protein complex of importance for the relative resistance of oculomotor nucleus motoneurons to degeneration?Folia Neuropathol. 2018;56(4):308-320. doi: 10.5114/fn.2018.80864. Folia Neuropathol. 2018. PMID: 30786668
-
Delayed disease onset and extended survival in the SOD1G93A rat model of amyotrophic lateral sclerosis after suppression of mutant SOD1 in the motor cortex.J Neurosci. 2014 Nov 19;34(47):15587-600. doi: 10.1523/JNEUROSCI.2037-14.2014. J Neurosci. 2014. PMID: 25411487 Free PMC article.
-
Utility of transcranial magnetic stimulation in delineating amyotrophic lateral sclerosis pathophysiology.Handb Clin Neurol. 2013;116:561-75. doi: 10.1016/B978-0-444-53497-2.00045-0. Handb Clin Neurol. 2013. PMID: 24112924 Review.
-
The Role of Iron in Amyotrophic Lateral Sclerosis.Adv Exp Med Biol. 2019;1173:145-152. doi: 10.1007/978-981-13-9589-5_8. Adv Exp Med Biol. 2019. PMID: 31456209 Review.
Cited by
-
Early-onset, conjugal, twin-discordant, and clusters of sporadic ALS: Pathway to discovery of etiology via lifetime exposome research.Front Neurosci. 2023 Feb 13;17:1005096. doi: 10.3389/fnins.2023.1005096. eCollection 2023. Front Neurosci. 2023. PMID: 36860617 Free PMC article. Review.
-
A rare case of conjugal amyotrophic lateral sclerosis.J Neurol. 2014 Jun;261(6):1216-7. doi: 10.1007/s00415-014-7330-y. Epub 2014 Apr 16. J Neurol. 2014. PMID: 24737169 No abstract available.
-
Conjugal amyotrophic lateral sclerosis: a case report from Scotland.BMC Neurol. 2017 Mar 29;17(1):64. doi: 10.1186/s12883-017-0847-9. BMC Neurol. 2017. PMID: 28356084 Free PMC article.
References
-
- Mitchell JD, Borasio GD. Amyotrophic lateral sclerosis. Lancet. 2007;369(9578):2031–2041. - PubMed
-
- Kiernan MC, Vucic S, Cheah BC, Turner MR, Eisen A, Hardiman O, Burrell JR, Zoing MC. Amyotrophic lateral sclerosis. Lancet. 2011;377(9769):942–955. - PubMed
-
- Kwiatkowski TJ, Jr, Bosco DA, Leclerc AL, Tamrazian E, Vanderburg CR, Russ C, Davis A, Gilchrist J, Kasarskis EJ, Munsat T, Valdmanis P, Rouleau GA, Hosler BA, Cortelli P, de Jong PJ, Yoshinaga Y, Haines JL, Pericak-Vance MA, Yan J, Ticozzi N, Siddique T, McKenna-Yasek D, Sapp PC, Horvitz HR, Landers JE, Brown RH., Jr Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis. Science. 2009;323(5918):1205–1208. - PubMed
-
- Renton AE, Majounie E, Waite A, Simón-Sánchez J, Rollinson S, Gibbs JR, Schymick JC, Laaksovirta H, van Swieten JC, Myllykangas L, Kalimo H, Paetau A, Abramzon Y, Remes AM, Kaganovich A, Scholz SW, Duckworth J, Ding J, Harmer DW, Hernandez DG, Johnson JO, Mok K, Ryten M, Trabzuni D, Guerreiro RJ, Orrell RW, Neal J, Murray A, Pearson J, Jansen IE, Sondervan D, Seelaar H, Blake D, Young K, Halliwell N, Callister JB, Toulson G, Richardson A, Gerhard A, Snowden J, Mann D, Neary D, Nalls MA, Peuralinna T, Jansson L, Isoviita VM, Kaivorinne AL, Hölttä-Vuori M, Ikonen E, Sulkava R, Benatar M, Wuu J, Chiò A, Restagno G, Borghero G, Sabatelli M, The ITALSGEN Consortium A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD. Neuron. 2011;72(2):257–268. - PMC - PubMed
LinkOut - more resources
Full Text Sources
Miscellaneous