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. 2008:2:88.
doi: 10.3332/ecancer.2008.88. Epub 2008 Aug 21.

Defeating cancer with antidepressants

J Lieb  1
Affiliations

Defeating cancer with antidepressants

J Lieb. Ecancermedicalscience. 2008.

Abstract

Prostaglandins are ephemeral, infinitesimal signallers self-regulating every cell in the body, including those sub-serving mood and immunity. At first, they were perceived as a master switch, but now are believed to regulate every component of cellular micro-anatomy and physiology, including those of the organelles, cytoskeleton, proteins, enzymes, nucleic acids and mitochondria. Prostaglandins are responsible, paradoxically, for cell function and dysfunction. Excessive prostaglandin synthesis depresses immune function and may induce cancer. An ideal anti-cancer agent would inhibit prostaglandins in such a manner as to shut down the pathogenesis of cancer. In this paper, I will show that antidepressants have such properties.

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