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. 2011 Oct;27(4):487-9.
doi: 10.4103/0970-1591.91438.

History of evidence-based medicine

Roger L Sur  1 , Philipp Dahm
Affiliations

History of evidence-based medicine

Roger L Sur et al. Indian J Urol. 2011 Oct.

Abstract

This essay reviews the historical circumstances surrounding the introduction and evolution of evidence-based medicine. Criticisms of the approach are also considered. Weaknesses of existing standards of clinical practice and efforts to bring more certainty to clinical decision making were the foundation for evidence-based medicine, which integrates epidemiology and medical research. Because of its utility in designing randomized clinical trials, assessing the quality of the literature, and applying medical research at the bedside, evidence-based medicine will continue to have a strong influence on everyday clinical practice.

Keywords: Evidence-based medicine; epidemiology; history; policy; randomized controlled trials; translational research.

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Conflict of interest statement

Conflict of Interest: None declared.

References

    1. Guyatt GH. Evidence-based medicine. ACP J Club. 1991;114:A–16. - PubMed
    1. Ingelfinger FJ, Relman AS, Finland M. Philadelphia (PA): W. B. Saunders; 1966. Controversy in Internal Medicine.
    1. Wennberg JE, Gittelsohn AM. Small area variations in health care delivery. Science. 1973;182:1102–8. - PubMed
    1. White KL. New York (NY): Springer-Verlag; 1991. Healing the Schism: Epidemiology, Medicine, and the Public's Health.
    1. Daly J. Los Angeles (CA): UC Press; 2005. Evidence Based Medicine and the Search for a Science of Clinical Care.