Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Mar 1;9(1):67-75.
doi: 10.2174/187569211794728850.

Personalized Medicine in the Age of Pharmacoproteomics: A Close up on India and Need for Social Science Engagement for Responsible Innovation in Post-Proteomic Biology

Affiliations

Personalized Medicine in the Age of Pharmacoproteomics: A Close up on India and Need for Social Science Engagement for Responsible Innovation in Post-Proteomic Biology

Panga Jaipal Reddy et al. Curr Pharmacogenomics Person Med. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

CONFLICT OF INTERESTS

None declared/applicable.

Figures

Figure 1
Figure 1
A map of the research institutions engaged in basic and clinical pharmacoproteomics research in India.
Figure 2
Figure 2. Continuum from genomic to proteomic microarray platforms and detection techniques
(a) The traditional genomic microarrays for gene expression studies print oligos or cDNA on substrates, (b) Protein microarrays are generated by immobilizing purified proteins on glass slide, (c) Nucleic Acid Programmable Protein Arrays, a novel cell-free based protein microarray platform where cDNA clones are immobilized to generate protein microarray by using in vitro transcription and translation system, (d) Antibody microarray is another advanced platform which is generated by immobilizing antibodies, (e) “Label-based detection” is traditional method used in microarray for signal detection by using radio-labeled, fluorescence, chemiluminiscence, (f) “Label-free detection” techniques such as surface Plasmon resonance and nanotube have been successfully integrated with microarrays.

Similar articles

Cited by

References

    1. Anderson NG, Matheson A, Anderson NL. Back to the future: the human protein index (HPI) and the agenda for post-proteomic biology. Proteomics. 2001;1:3–12. - PubMed
    1. Legrain P, Aebersold R, Archakov A, et al. The human proteome project: Current state and future direction. Mol Cell Proteomics. 2011 Apr 29; [Epub ahead of print] - PubMed
    1. Paik YK, Kim H, Lee EY, et al. Overview and introduction to clinical proteomics. Methods Mol Biol. 2008;428:1–31. - PubMed
    1. Kalow W, Ozdemir V, Tang BK, et al. The science of pharmacological variability: an essay. Clin Pharmacol Ther. 1999;66(5):445–7. - PubMed
    1. Ozdemir V, Suarez-Kurtz G, Stenne R, et al. Risk assessment and communication tools for genotype associations with multifactorial phenotypes: the concept of “edge effect” and cultivating an ethical bridge between omics innovations and society. OMICS. 2009;13(1):43–61. - PMC - PubMed

LinkOut - more resources