The aryl hydrocarbon receptor: a sentinel safeguarding the survival of immune cells in the gut
- PMID: 22284414
- DOI: 10.1016/j.immuni.2012.01.004
The aryl hydrocarbon receptor: a sentinel safeguarding the survival of immune cells in the gut
Abstract
Innate lymphoid cells (ILCs) regulate the epithelial barrier function and immunity in the gut. How ILC numbers are maintained is unknown. In this issue of Immunity, Qiu et al. (2012) report that the transcription factor aryl hydrocarbon receptor controls survival and function of gut-residing ILCs.
Copyright © 2012 Elsevier Inc. All rights reserved.
Comment on
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The aryl hydrocarbon receptor regulates gut immunity through modulation of innate lymphoid cells.Immunity. 2012 Jan 27;36(1):92-104. doi: 10.1016/j.immuni.2011.11.011. Epub 2011 Dec 15. Immunity. 2012. PMID: 22177117 Free PMC article.
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