The numerology of T cell functional diversity
- PMID: 22284416
- PMCID: PMC3732210
- DOI: 10.1016/j.immuni.2012.01.006
The numerology of T cell functional diversity
Abstract
Memory T cells are heterogeneous in phenotype and function. In this issue of Immunity, Newell et al. (2012) use a new flow cytometry platform to show that the functional heterogeneity of the human T cell compartment is even greater than previously thought.
Copyright © 2012 Elsevier Inc. All rights reserved.
Comment in
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Memory T cells: new insights into the molecular basis of sensitivity and heterogeneity.Am J Transplant. 2012 Jun;12(6):1361. doi: 10.1111/j.1600-6143.2012.04151.x. Am J Transplant. 2012. PMID: 22642469 No abstract available.
Comment on
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Cytometry by time-of-flight shows combinatorial cytokine expression and virus-specific cell niches within a continuum of CD8+ T cell phenotypes.Immunity. 2012 Jan 27;36(1):142-52. doi: 10.1016/j.immuni.2012.01.002. Immunity. 2012. PMID: 22265676 Free PMC article.
References
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- Flatz L, Roychoudhuri R, Honda M, Filali-Mouhim A, Goulet J-P, Kettaf N, Lin M, Roederer M, Haddad EK, Sékaly RP, et al. Single-cell gene-expression profiling reveals qualitatively distinct CD8 T cells elicited by different gene-based vaccines. Proceedings of the National Academy of Sciences. 2011;108:5724–5729. - PMC - PubMed
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