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Review
. 2012 Feb;22(1):33-55, vii-viii.
doi: 10.1016/j.nic.2011.11.007.

Structural neuroimaging in aging and Alzheimer's disease

Meike W Vernooij  1 , Marion Smits
Affiliations
Review

Structural neuroimaging in aging and Alzheimer's disease

Meike W Vernooij et al. Neuroimaging Clin N Am. 2012 Feb.

Abstract

The role of structural neuroimaging in the diagnosis of Alzheimer's disease (AD) is becoming increasingly important. As a consequence, a basic understanding of what are normal brain changes in aging is key to be able to recognize what is abnormal. The first part of this article discusses normal versus pathologic brain aging, focusing on qualitative and quantitative magnetic resonance (MR) imaging markers. In the second part, the role of MR imaging in the (differential) diagnosis of AD is reviewed.

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