Different virucidal activities of hyperbranched quaternary ammonium coatings on poliovirus and influenza virus

Abstract

Virucidal activity of immobilized quaternary ammonium compounds (IQACs) coated onto glass and plastic surfaces was tested against enveloped influenza A (H1N1) virus and nonenveloped poliovirus Sabin1. The IQACs tested were virucidal against the influenza virus within 2 min, but no virucidal effect against poliovirus was found in 6 h.

Fig 1

Environmental decay of poliovirus and influenza virus at room temperature. PV-P is poliovirus on plastic, PV-G is poliovirus on glass, Inf-P is influenza virus on plastic, and Inf-G is influenza virus on glass. Data are from 2 experiments with duplicate samples per experiment, and error bars indicate standard deviations (SD).

Fig 2

Reduction of infective poliovirus and influenza virus by different IQACs after 1 h of exposure at room temperature. Data are from 2 experiments with duplicate samples per experiment, and error bars indicate SD.

Fig 3

Reduction of PCRU of influenza virus by different IQACs after 1 h of exposure at room temperature. Data are from 2 experiments with duplicate samples per experiment, and error bars indicate SD.