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Review
. 2012 Feb;12(2):199-208.
doi: 10.1586/ern.11.99.

Epidemiology and prevention of stroke: a worldwide perspective

Affiliations
Review

Epidemiology and prevention of stroke: a worldwide perspective

Elena V Kuklina et al. Expert Rev Neurother. 2012 Feb.

Abstract

This paper reviews how epidemiological studies during the last 5 years have advanced our knowledge in addressing the global stroke epidemic. The specific objectives were to review the current evidence supporting management of ten major modifiable risk factors for prevention of stroke: hypertension, current smoking, diabetes, obesity, poor diet, physical inactivity, atrial fibrillation, excessive alcohol consumption, abnormal lipid profile and psychosocial stress/depression.

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Conflict of interest statement

Financial & competing interests disclosure

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript.

No writing assistance was utilized in the production of this manuscript.

References

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    1. WHO. The Global Burden of Disease: 2004 Update. Geneva, Switzerland: WHO; 2008.
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    1. Goldstein LB, Bushnell CD, Adams RJ, et al. Guidelines for the primary prevention of stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2011;42(2):517–584. •• Provides an overview of the evidence on established and emerging risk factors for stroke to provide evidence-based recommendations for the reduction of risk of a first stroke.

    1. Law MR, Morris JK, Wald NJ. Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies. BMJ. 2009;338:b1665. • Meta-analysis reporting the quantitative efficacy of different classes of blood pressure-lowering drugs in preventing stroke.

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