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. 2012 Mar 5;13(4):515-9.
doi: 10.1002/cbic.201100800. Epub 2012 Feb 2.

Design of photocontrolled RNA-binding peptidomimetics

Robert J Mart  1 , Piotr Wysoczański, Sabine Kneissl, Antonio Ricci, Andrea Brancale, Rudolf K Allemann
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Design of photocontrolled RNA-binding peptidomimetics

Robert J Mart et al. Chembiochem. .

Abstract

Positively constrained: the first examples of photocontrolled RNA binding peptides are described. The large number of positively charged sides chains in the Rev response element (RRE) of an HIV type I targeting α-helix imposes constraints on the choice of azobenzene-derived crosslinker.

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