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Comment
. 2012 Feb 3;10(2):111-2.
doi: 10.1016/j.stem.2012.01.002.

Periostin: a bridge between cancer stem cells and their metastatic niche

Zhe Wang  1 , Gaoliang Ouyang
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Periostin: a bridge between cancer stem cells and their metastatic niche

Zhe Wang et al. Cell Stem Cell. .
Free article

Abstract

Only a minority of cancer cells have the potential to initiate metastatic growth, but the factors that limit metastatic colonization remain mostly unknown. Malanchi et al. (2012) recently demonstrated that stromal periostin is crucial for metastatic colonization by regulating the interactions between breast cancer stem cells and their metastatic niche.

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