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. 2012 Mar 12;51(11):2708-11.
doi: 10.1002/anie.201107802. Epub 2012 Feb 3.

Enantioselective iridium-catalyzed hydrogenation of β,γ-unsaturated carboxylic acids: an efficient approach to chiral 4-alkyl-4-aryl butanoic acids

Song Song  1 , Shou-Fei Zhu, Shuang Yang, Shen Li, Qi-Lin Zhou
Affiliations

Enantioselective iridium-catalyzed hydrogenation of β,γ-unsaturated carboxylic acids: an efficient approach to chiral 4-alkyl-4-aryl butanoic acids

Song Song et al. Angew Chem Int Ed Engl. .

Abstract

Chiral acids: a highly enantioselective iridium-catalyzed hydrogenation of β,γ-unsaturated carboxylic acids is developed for the preparation of chiral 4-alkyl-4-aryl butanoic acids.

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