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Comparative Study
. 2012 Jun;101(6):562-8.
doi: 10.1111/j.1651-2227.2012.02626.x. Epub 2012 Mar 6.

The validity of biochemical markers in metabolic bone disease in preterm infants: a systematic review

Fenna Visser  1 , Arwen J Sprij, Frank Brus
Affiliations
Comparative Study

The validity of biochemical markers in metabolic bone disease in preterm infants: a systematic review

Fenna Visser et al. Acta Paediatr. 2012 Jun.

Abstract

To establish the validity of biochemical markers of metabolic bone disease (MBD) in preterm infants.

Conclusion: There is insufficient evidence that any of the frequently used serum measurements are valid biochemical markers of MBD in preterm infants. Increased urinary calcium concentration may be a valid biochemical marker, but more research is necessary to confirm this.

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