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Review
. 2012 May;14(3):189-95.
doi: 10.1016/j.ymben.2012.01.004. Epub 2012 Feb 1.

Synthetic biology and the development of tools for metabolic engineering

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Review

Synthetic biology and the development of tools for metabolic engineering

Jay D Keasling. Metab Eng. 2012 May.

Abstract

Synthetic biology can significantly advance metabolic engineering by contributing tools (minimal hosts, vectors, genetic controllers, characterized enzymes). The development of these tools significantly reduced the costs and time to develop the antimalarial drug artemisinin, but the availability of more tools could have reduced these costs substantially.

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