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Case Reports
. 2012 Feb;14(2):147-50.
doi: 10.1177/1098612X11429226.

Amputation for histiocytic sarcoma in a cat

Takahiro Teshima  1 , Takashi Hata, Yoko Nezu, Masaki Michishita, Hirotaka Matsumoto, Hisashi Mizutani, Kimimasa Takahashi, Hidekazu Koyama
Affiliations
Case Reports

Amputation for histiocytic sarcoma in a cat

Takahiro Teshima et al. J Feline Med Surg. 2012 Feb.

Abstract

A 9-year-old spayed female domestic shorthair cat presented with a skin lesion of the left tarsus. The lesion was biopsied and, based on the microscopic appearance and immunohistochemical characteristics, histiocytic sarcoma was diagnosed. Amputation was performed with improved demeanor seen postoperatively. However, between 44 and 60 days following the surgery, relapse of skin lesions appeared in multiple locations, including at the previous amputation site, and euthanasia was elected. This is the first report of a histiocytic sarcoma treated with amputation in a cat.

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Conflict of interest statement

The authors declare that there is no conflict of interest.

Figures

Figure 1
Figure 1
Histopathology of the tarsus. The mass is composed of a proliferation of highly pleomorphic cells. Haematoxylin and eosin stain (A). Pleomorphic cells are immunopositive for HLA-DR (B) and Iba1 (C). ×1000 magnification. Bar = 50 µm
Figure 2
Figure 2
Gross and histological appearance of the skin lesions at recurrence. Gross appearance of the skin lesions at the previous site of amputation (A) and the toe of right hindlimb (B). (C) Pleomorphic histiocytes at the previous site of amputation. Haematoxylin and eosin stain; ×1000 magnification. Bar = 50 µm
See this image and copyright information in PMC

References

    1. Affolter VK, Moore PF. Localized and disseminated histiocytic sarcoma of dendritic cell origin in dogs. Vet Pathol 2002; 39: 74–83. - PubMed
    1. Affolter VK, Moore PF. Feline progressive histiocytosis. Vet Pathol 2006; 43: 646–55. - PubMed
    1. Imam A, Stathopoulos E, Taylor CR. BLA.36: a glycoprotein specifically expressed on the surface of Hodgkin’s and B cells. Anticancer Res 1990; 10: 1095–104. - PubMed
    1. Smoliga J, Schatzberg S, Peters J, et al. . Myelopathy caused by a histiocytic sarcoma in a cat. J Small Anim Pract 2005; 46: 34–8. - PubMed
    1. Imai Y, Ibata I, Ito D, et al. . A novel gene iba1 in the major histocompatibility complex class III region encoding an EF hand protein expressed in a monocytic lineage. Biochem Biophys Res Commun 1996; 224: 855–62. - PubMed

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