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. 2012 Mar 15;24(11):1418-23.
doi: 10.1002/adma.201104714. Epub 2012 Feb 9.

Mesoporous silica-coated gold nanorods as a light-mediated multifunctional theranostic platform for cancer treatment

Zhenjiang Zhang  1 , Liming Wang, Jing Wang, Xiumei Jiang, Xiaohui Li, Zhijian Hu, Yinglu Ji, Xiaochun Wu, Chunying Chen
Affiliations

Mesoporous silica-coated gold nanorods as a light-mediated multifunctional theranostic platform for cancer treatment

Zhenjiang Zhang et al. Adv Mater. .

Erratum in

Abstract

Mesoporous silica-coated gold nanorods (Au@SiO(2)) are developed as a promising and versatile theranostic platform for cancer treatment. Intracellular localization of Au@SiO(2) is visualized through two-photon imaging. With doxorubicin hydrochloride loaded, Au@SiO(2)-DOX show two light-mediated therapeutic modes: low power density laser-triggered drug release for chemotherapy, and high power density laser-induced hyperthermia, which suggest the potential for in-vivo applications.

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