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Comment
. 2012 Feb 7;22(3):R87-9.
doi: 10.1016/j.cub.2011.12.030.

Calcium signaling: deciphering the calcium-NFAT pathway

James W Putney  1
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Calcium signaling: deciphering the calcium-NFAT pathway

James W Putney. Curr Biol. .
Free article

Abstract

Rapid cellular calcium oscillations activate gene expression hours later. How this temporal response amplification is achieved has until now been largely a mystery. An elegant combination of experimental strategies and a model that encompasses non-linear inputs and outputs now sheds new light on this long-standing problem.

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