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Comment
. 2012 Feb 9;119(6):1331-2.
doi: 10.1182/blood-2011-12-393496.

Exciting new murine model of cGVHD

Bryon D Johnson  1
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Free article
Comment

Exciting new murine model of cGVHD

Bryon D Johnson. Blood. .
Free article

Abstract

In this issue of Blood, Srinivasan et al report that mice conditioned for allogeneic hematopoietic stem cell transplantation with cyclophosphamide and total body irradiation develop wide-spectrum manifestations of chronic graft-versus-host disease (cGVHD).1 This represents an exciting new preclinical model that can be used to uncover mechanisms of cGVHD and test interventional therapies.

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