Early congenital syphilis presenting with skin eruption alone: a case report

Abstract

Congenital syphilis is one of the most well-known congenital infections, yet it remains a worldwide public health problem. Congenital syphilis can involve any organ system and present with various symptoms. However, early diagnosis of congenital syphilis is difficult because more than half of the affected infants are asymptomatic, and the signs in symptomatic infants may be subtle and nonspecific. Here, we report a case of congenital syphilis with only a skin rash, which led to a delay in diagnosis. This case indicates that congenital syphilis should be considered throughout early childhood.

Keywords: Congenital syphilis; Skin rash.

Fig. 1

Generalized erythematous, targetoid, scaly macules, papules, and pustules (A), and desquamation of the patient's hand (B).

Fig. 2

Radiographic examination of the long bones demonstrated diaphyseal periostitis, indicating syphilitic changes.