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. 2012 Nov;40(9):880-2.
doi: 10.1016/j.ajic.2011.11.004. Epub 2012 Feb 10.

Aldehyde-resistant mycobacteria bacteria associated with the use of endoscope reprocessing systems

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Aldehyde-resistant mycobacteria bacteria associated with the use of endoscope reprocessing systems

Christopher W Fisher et al. Am J Infect Control. 2012 Nov.

Abstract

Bacteria can develop resistance to antibiotics, but little is known about their ability to increase resistance to chemical disinfectants. This study randomly sampled 3 automated endoscope reprocessors in the United States using aldehydes for endoscope disinfection. Bacterial contamination was found after disinfection in all automated endoscope reprocessors, and some mycobacteria isolates demonstrated significant resistance to glutaraldehyde and ortho-phthaldehyde disinfectants. Bacteria can survive aldehyde-based disinfection and may pose a cross-contamination risk to patients.

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Figures

Figure 1
Figure 1
Sensitivity of isolates to aldehyde disinfection (average log reduction shown). Note, only one control (M. gordonae) and some of the strains showing significant resistance are shown; culture collection strains of the other bacteria species identified where tested and did not show greater resistance to disinfection than the M. gordonae control strain.

References

    1. McDonnell G. Antisepsis, Disinfection, and Sterilization: Types, Action, and Resistance. Washington DC: ASM Press; 2007.
    1. Griffiths PA, Babb JR, Bradley CR, Fraise AP. Glutaraldehyde resistant Mycobacterium chelonae from endoscope washer disinfectors. J Appl Microbiol. 1997;82:519–526. - PubMed
    1. Nomura K, Ogawa M, Miyamoto H, Muratani T, Taniguchi H. Antibiotic susceptibility of glutaraldehyde-tolerant Mycobacterium chelonae from bronchoscope washing machines. Am J Infect Control. 2004;32(4):185–188. - PubMed
    1. van Klingeren B, Pullen W. Glutaraldehyde resistant mycobacteria from endoscope washers. J Hosp Infect. 1993;25(2):147–149. - PubMed
    1. Duarte RS, Lourenço MC, de Fonseca LS, Leão SC, de Amorim EL, et al. Epidemic of postsurgical infections caused by Mycobacterium massiliense. J Clin Microbiol. 2009;47(7):2149–2155. - PMC - PubMed

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