The porous borders of the protein world
- PMID: 22325767
- DOI: 10.1016/j.str.2012.01.015
The porous borders of the protein world
Abstract
Fold switching may play a role in the evolution of new protein folds and functions. He et al., in this issue of Structure, use protein design to illustrate that the same drastic change in a protein fold can occur via multiple different mutational pathways.
Copyright © 2012 Elsevier Ltd. All rights reserved.
Comment on
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Mutational tipping points for switching protein folds and functions.Structure. 2012 Feb 8;20(2):283-91. doi: 10.1016/j.str.2011.11.018. Structure. 2012. PMID: 22325777 Free PMC article.
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