METabolic adaptations in the tumor MYCroenvironment
- PMID: 22326214
- DOI: 10.1016/j.cmet.2012.01.005
METabolic adaptations in the tumor MYCroenvironment
Abstract
In this issue of Cell Metabolism, Yuneva et al. (2012) use mouse cancer models to characterize tumor nutrient metabolism in vivo. This study suggests that the metabolic phenotype of cancer cells is not only determined by the mutational status of specific oncogenes but is also influenced by the cell of origin and tumor microenvironment.
Copyright © 2012 Elsevier Inc. All rights reserved.
Comment on
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The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type.Cell Metab. 2012 Feb 8;15(2):157-70. doi: 10.1016/j.cmet.2011.12.015. Cell Metab. 2012. PMID: 22326218 Free PMC article.
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